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Computational Design of Miniproteins as SARS-CoV-2 Therapeutic Inhibitors

A rational therapeutic strategy is urgently needed for combating SARS-CoV-2 infection. Viral infection initiates when the SARS-CoV-2 receptor-binding domain (RBD) binds to the ACE2 receptor, and thus, inhibiting RBD is a promising therapeutic for blocking viral entry. In this study, the structure of...

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Detalles Bibliográficos
Autores principales: Jawad, Bahaa, Adhikari, Puja, Cheng, Kun, Podgornik, Rudolf, Ching, Wai-Yim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776159/
https://www.ncbi.nlm.nih.gov/pubmed/35055023
http://dx.doi.org/10.3390/ijms23020838