Albumin Expands Albumin Reabsorption Capacity in Proximal Tubule Epithelial Cells through a Positive Feedback Loop between AKT and Megalin

Renal proximal tubule cells (PTECs) act as urine gatekeepers, constantly and efficiently avoiding urinary protein waste through receptor-mediated endocytosis. Despite its importance, little is known about how this process is modulated in physiologic conditions. Data suggest that the phosphoinositide...

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Detalles Bibliográficos
Autores principales: Silva-Aguiar, Rodrigo P., Peruchetti, Diogo B., Florentino, Lucas S., Takiya, Christina M., Marzolo, María-Paz, Dias, Wagner B., Pinheiro, Ana Acacia S., Caruso-Neves, Celso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776186/
https://www.ncbi.nlm.nih.gov/pubmed/35055044
http://dx.doi.org/10.3390/ijms23020848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776186/
https://www.ncbi.nlm.nih.gov/pubmed/35055044
http://dx.doi.org/10.3390/ijms23020848

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