Next Generation Sequencing Detects Premeiotic Errors in Human Oocytes

Autosomal aneuploidy is the leading cause of embryonic and foetal death in humans. This arises mainly from errors in meiosis I or II of oogenesis. A largely ignored source of error stems from germinal mosaicism, which leads to premeiotic aneuploidy. Molecular cytogenetic studies employing metaphase...

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Detalles Bibliográficos
Autores principales: Ghevaria, Harita, SenGupta, Sioban, Naja, Roy, Odia, Rabi, Exeter, Holly, Serhal, Paul, Gonzalez, Xavier Viñals, Sun, Xuhui, Delhanty, Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776218/
https://www.ncbi.nlm.nih.gov/pubmed/35054849
http://dx.doi.org/10.3390/ijms23020665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776218/
https://www.ncbi.nlm.nih.gov/pubmed/35054849
http://dx.doi.org/10.3390/ijms23020665

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