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The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme

Avermectins are macrocyclic lactones with anthelmintic activity. Recently, they were found to be effective against Mycobacterium tuberculosis, which accounts for one third of the worldwide deaths from antimicrobial resistance. However, their anti-mycobacterial mode of action remains to be elucidated...

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Detalles Bibliográficos
Autores principales: Ezquerra-Aznárez, José Manuel, Degiacomi, Giulia, Gašparovič, Henrich, Stelitano, Giovanni, Sammartino, Josè Camilla, Korduláková, Jana, Governa, Paolo, Manetti, Fabrizio, Pasca, Maria Rosalia, Chiarelli, Laurent Roberto, Ramón-García, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776228/
https://www.ncbi.nlm.nih.gov/pubmed/35054958
http://dx.doi.org/10.3390/ijms23020771