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Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography
Mechanosensory transduction (MT), the conversion of mechanical stimuli into electrical signals, underpins hearing and balance and is carried out within hair cells in the inner ear. Hair cells harbor actin-filled stereocilia, arranged in rows of descending heights, where the tips of stereocilia are c...
Autores principales: | Elferich, Johannes, Clark, Sarah, Ge, Jingpeng, Goehring, April, Matsui, Aya, Gouaux, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776254/ https://www.ncbi.nlm.nih.gov/pubmed/34964715 http://dx.doi.org/10.7554/eLife.74512 |
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