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Overexpression of Parkin in clear cell renal cell carcinoma decreases tumor aggressiveness by regulating CKS2 levels
Low expression levels of the E3 ubiquitin-protein ligase Parkin (PARK2) are exhibited in several cancer entities, including clear cell renal cell carcinoma (ccRCC), and are associated with poor prognosis; however, PARK2 can also function as a tumor suppressor gene. The aim of the present study was t...
Autores principales: | Esser, Laura Kristin, Branchi, Vittorio, Shakeri, Farhad, Simon, Adrian Georg, Stephan, Carsten, Kristiansen, Glen, Buness, Andreas, Schorle, Hubert, Toma, Marieta Ioana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776329/ https://www.ncbi.nlm.nih.gov/pubmed/35059737 http://dx.doi.org/10.3892/ijo.2022.5310 |
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