The Emerging Role of c-Met in Carcinogenesis and Clinical Implications as a Possible Therapeutic Target

BACKGROUND: c-MET is a receptor tyrosine kinase receptor (RTK) for the hepatocyte growth factor (HGF). The binding of HGF to c-MET regulates several cellular functions: differentiation, proliferation, epithelial cell motility, angiogenesis, and epithelial-mesenchymal transition (EMT). Moreover, it i...

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Detalles Bibliográficos
Autores principales: Faiella, Antonio, Riccardi, Ferdinando, Cartenì, Giacomo, Chiurazzi, Martina, Onofrio, Livia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776431/
https://www.ncbi.nlm.nih.gov/pubmed/35069735
http://dx.doi.org/10.1155/2022/5179182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776431/
https://www.ncbi.nlm.nih.gov/pubmed/35069735
http://dx.doi.org/10.1155/2022/5179182

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