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The Emerging Role of c-Met in Carcinogenesis and Clinical Implications as a Possible Therapeutic Target
BACKGROUND: c-MET is a receptor tyrosine kinase receptor (RTK) for the hepatocyte growth factor (HGF). The binding of HGF to c-MET regulates several cellular functions: differentiation, proliferation, epithelial cell motility, angiogenesis, and epithelial-mesenchymal transition (EMT). Moreover, it i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776431/ https://www.ncbi.nlm.nih.gov/pubmed/35069735 http://dx.doi.org/10.1155/2022/5179182 |