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SOX2 knockdown with siRNA reverses cisplatin resistance in NSCLC by regulating APE1 signaling

SOX2 is related to drug resistance in many types of cancer, including lung cancer. Herein, we investigated the role of SOX2 and its regulatory signaling in cisplatin-treated non-small-cell lung cancer (NSCLC). The effects of SOX2 on cell viability, proliferation, and apoptosis were evaluated in vitr...

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Detalles Bibliográficos
Autores principales: Chen, Tai-yu, Zhou, Ji, Li, Peng-cheng, Tang, Chun-han, Xu, Ke, Li, Tao, Ren, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776672/
https://www.ncbi.nlm.nih.gov/pubmed/35059870
http://dx.doi.org/10.1007/s12032-021-01626-3