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SOX2 knockdown with siRNA reverses cisplatin resistance in NSCLC by regulating APE1 signaling
SOX2 is related to drug resistance in many types of cancer, including lung cancer. Herein, we investigated the role of SOX2 and its regulatory signaling in cisplatin-treated non-small-cell lung cancer (NSCLC). The effects of SOX2 on cell viability, proliferation, and apoptosis were evaluated in vitr...
Autores principales: | Chen, Tai-yu, Zhou, Ji, Li, Peng-cheng, Tang, Chun-han, Xu, Ke, Li, Tao, Ren, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776672/ https://www.ncbi.nlm.nih.gov/pubmed/35059870 http://dx.doi.org/10.1007/s12032-021-01626-3 |
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