Survival benefit with adjuvant chemotherapy in stage III microsatellite-high/deficient mismatch repair colon cancer: a systematic review and meta-analysis

Clinical observations have demonstrated that microsatellite instability-high (MSI-H) and/or deficient MMR (dMMR) status are associated with favorable prognosis and no benefit from 5-Fluorouracil (5-FU)-based adjuvant chemotherapy in patients with resected stage II colorectal cancer (CRC). This study...

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Detalles Bibliográficos
Autores principales: Tomasello, Gianluca, Ghidini, Michele, Galassi, Barbara, Grossi, Francesco, Luciani, Andrea, Petrelli, Fausto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776729/
https://www.ncbi.nlm.nih.gov/pubmed/35058539
http://dx.doi.org/10.1038/s41598-022-05065-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776729/
https://www.ncbi.nlm.nih.gov/pubmed/35058539
http://dx.doi.org/10.1038/s41598-022-05065-6

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