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Tumor radioresistance caused by radiation-induced changes of stem-like cell content and sub-lethal damage repair capability

Cancer stem-like cells (CSCs) within solid tumors exhibit radioresistance, leading to recurrence and distant metastasis after radiotherapy. To experimentally study the characteristics of CSCs, radioresistant cell lines were successfully established using fractionated X-ray irradiation. The fundament...

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Detalles Bibliográficos
Autores principales: Fukui, Roman, Saga, Ryo, Matsuya, Yusuke, Tomita, Kazuo, Kuwahara, Yoshikazu, Ohuchi, Kentaro, Sato, Tomoaki, Okumura, Kazuhiko, Date, Hiroyuki, Fukumoto, Manabu, Hosokawa, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776741/
https://www.ncbi.nlm.nih.gov/pubmed/35058559
http://dx.doi.org/10.1038/s41598-022-05172-4