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Tumor radioresistance caused by radiation-induced changes of stem-like cell content and sub-lethal damage repair capability
Cancer stem-like cells (CSCs) within solid tumors exhibit radioresistance, leading to recurrence and distant metastasis after radiotherapy. To experimentally study the characteristics of CSCs, radioresistant cell lines were successfully established using fractionated X-ray irradiation. The fundament...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776741/ https://www.ncbi.nlm.nih.gov/pubmed/35058559 http://dx.doi.org/10.1038/s41598-022-05172-4 |