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A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family

Eukaryotic deubiquitinases are important regulators of ubiquitin signaling and can be subdivided into several structurally distinct classes. The ZUFSP family, with ZUP1 as its sole human member, has a modular architecture with a core catalytic domain highly active against the ubiquitin-derived pepti...

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Detalles Bibliográficos
Autores principales: Hermanns, Thomas, Pichlo, Christian, Baumann, Ulrich, Hofmann, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776766/
https://www.ncbi.nlm.nih.gov/pubmed/35058438
http://dx.doi.org/10.1038/s41467-022-28049-6