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A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family
Eukaryotic deubiquitinases are important regulators of ubiquitin signaling and can be subdivided into several structurally distinct classes. The ZUFSP family, with ZUP1 as its sole human member, has a modular architecture with a core catalytic domain highly active against the ubiquitin-derived pepti...
Autores principales: | Hermanns, Thomas, Pichlo, Christian, Baumann, Ulrich, Hofmann, Kay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776766/ https://www.ncbi.nlm.nih.gov/pubmed/35058438 http://dx.doi.org/10.1038/s41467-022-28049-6 |
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