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Structure and mechanism of the RNA dependent RNase Cas13a from Rhodobacter capsulatus
Cas13a are single-molecule effectors of the Class II, Type VI family of CRISPR-Cas systems that are part of the bacterial and archaeal defense systems. These RNA-guided and RNA-activated RNA endonucleases are characterized by their ability to cleave target RNAs complementary to the crRNA-spacer sequ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776769/ https://www.ncbi.nlm.nih.gov/pubmed/35058543 http://dx.doi.org/10.1038/s42003-022-03025-4 |