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Structure and mechanism of the RNA dependent RNase Cas13a from Rhodobacter capsulatus

Cas13a are single-molecule effectors of the Class II, Type VI family of CRISPR-Cas systems that are part of the bacterial and archaeal defense systems. These RNA-guided and RNA-activated RNA endonucleases are characterized by their ability to cleave target RNAs complementary to the crRNA-spacer sequ...

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Detalles Bibliográficos
Autores principales:	Kick, Leonhard M., von Wrisberg, Marie-Kristin, Runtsch, Leander S., Schneider, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776769/ https://www.ncbi.nlm.nih.gov/pubmed/35058543 http://dx.doi.org/10.1038/s42003-022-03025-4

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