GDF15 promotes prostate cancer bone metastasis and colonization through osteoblastic CCL2 and RANKL activation

Bone metastases occur in patients with advanced-stage prostate cancer (PCa). The cell-cell interaction between PCa and the bone microenvironment forms a vicious cycle that modulates the bone microenvironment, increases bone deformities, and drives tumor growth in the bone. However, the molecular mec...

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Detalles Bibliográficos
Autores principales: Siddiqui, Jawed Akhtar, Seshacharyulu, Parthasarathy, Muniyan, Sakthivel, Pothuraju, Ramesh, Khan, Parvez, Vengoji, Raghupathy, Chaudhary, Sanjib, Maurya, Shailendra Kumar, Lele, Subodh Mukund, Jain, Maneesh, Datta, Kaustubh, Nasser, Mohd Wasim, Batra, Surinder Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776828/
https://www.ncbi.nlm.nih.gov/pubmed/35058441
http://dx.doi.org/10.1038/s41413-021-00178-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776828/
https://www.ncbi.nlm.nih.gov/pubmed/35058441
http://dx.doi.org/10.1038/s41413-021-00178-6

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