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Process intensification for the continuous production of an antimicrobial peptide in stably-transformed Sf-9 insect cells

The antibiotic resistance crisis has prompted research into alternative candidates such as antimicrobial peptides (AMPs). However, the demand for such molecules can only be met by continuous production processes, which achieve high product yields and offer compatibility with the Quality-by-Design in...

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Detalles Bibliográficos
Autores principales: Käßer, Lukas, Rotter, Maximilian, Coletta, Luca, Salzig, Denise, Czermak, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776851/
https://www.ncbi.nlm.nih.gov/pubmed/35058492
http://dx.doi.org/10.1038/s41598-022-04931-7