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Using Cryo-ET to distinguish platelets during pre-acute myeloid leukemia from steady state hematopoiesis
Early diagnosis of acute myeloid leukemia (AML) in the pre-leukemic stage remains a clinical challenge, as pre-leukemic patients show no symptoms, lacking any known morphological or numerical abnormalities in blood cells. Here, we demonstrate that platelets with structurally abnormal mitochondria em...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776871/ https://www.ncbi.nlm.nih.gov/pubmed/35058565 http://dx.doi.org/10.1038/s42003-022-03009-4 |