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Using Cryo-ET to distinguish platelets during pre-acute myeloid leukemia from steady state hematopoiesis

Early diagnosis of acute myeloid leukemia (AML) in the pre-leukemic stage remains a clinical challenge, as pre-leukemic patients show no symptoms, lacking any known morphological or numerical abnormalities in blood cells. Here, we demonstrate that platelets with structurally abnormal mitochondria em...

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Detalles Bibliográficos
Autores principales: Wang, Yuewei, Huo, Tong, Tseng, Yu-Jung, Dang, Lan, Yu, Zhili, Yu, Wenjuan, Foulks, Zachary, Murdaugh, Rebecca L., Ludtke, Steven J., Nakada, Daisuke, Wang, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776871/
https://www.ncbi.nlm.nih.gov/pubmed/35058565
http://dx.doi.org/10.1038/s42003-022-03009-4