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Essential function of adaptor protein Nck1 in platelet-derived growth factor receptor signaling in human lens epithelial cells

Binding of platelet-derived growth factor-BB (PDGF-BB) to its cognate receptor (PDGFR) promotes lens epithelial cell (LEC) proliferation and migration. After cataract surgery, these LEC behaviors have been proposed as an influential cause of posterior capsule opacification (PCO). Stimulated PDFGR un...

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Detalles Bibliográficos
Autores principales: Paensuwan, Pussadee, Ngoenkam, Jatuporn, Wangteeraprasert, Apirath, Pongcharoen, Sutatip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776929/
https://www.ncbi.nlm.nih.gov/pubmed/35058548
http://dx.doi.org/10.1038/s41598-022-05183-1