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Essential function of adaptor protein Nck1 in platelet-derived growth factor receptor signaling in human lens epithelial cells
Binding of platelet-derived growth factor-BB (PDGF-BB) to its cognate receptor (PDGFR) promotes lens epithelial cell (LEC) proliferation and migration. After cataract surgery, these LEC behaviors have been proposed as an influential cause of posterior capsule opacification (PCO). Stimulated PDFGR un...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776929/ https://www.ncbi.nlm.nih.gov/pubmed/35058548 http://dx.doi.org/10.1038/s41598-022-05183-1 |