Integration of a miniaturized DMMB assay with high-throughput screening for identifying regulators of proteoglycan metabolism

Defective biosynthesis or function of proteoglycans causes pathological conditions in a variety of tissue systems. Osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by progressive cartilage destruction caused by imbalanced proteoglycan synthesis and degradation. Identifyin...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Tsui, Yuen-kee, Yu, Mengqi, Lyu, Minmin, Cheung, Kenneth, Kao, Richard, Leung, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776954/
https://www.ncbi.nlm.nih.gov/pubmed/35058478
http://dx.doi.org/10.1038/s41598-022-04805-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776954/
https://www.ncbi.nlm.nih.gov/pubmed/35058478
http://dx.doi.org/10.1038/s41598-022-04805-y

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