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RTA and LANA Competitively Regulate let-7a/RBPJ Signal to Control KSHV Replication

The recombination signal binding protein for immunoglobulin kappa J region (RBPJ) has a dual effect on Kaposi’s sarcoma-associated herpesvirus (KSHV) replication. RBPJ interaction with replication and transcription activator (RTA) is essential for lytic replication, while the interaction with latenc...

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Detalles Bibliográficos
Autores principales: Di, Chunhong, Zheng, Guoxia, Zhang, Yunheng, Tong, Enyu, Ren, Yanli, Hong, Yu, Song, Yang, Chen, Rong, Tan, Xiaohua, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777081/
https://www.ncbi.nlm.nih.gov/pubmed/35069510
http://dx.doi.org/10.3389/fmicb.2021.804215