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Complement Inhibition Alleviates Cholestatic Liver Injury Through Mediating Macrophage Infiltration and Function in Mice

BACKGROUND AND AIMS: Cholestatic liver injury (CLI), which is associated with inflammatory reactions and oxidative stress, is a serious risk factor for postoperative complications. Complement system is involved in a wide range of liver disorders, including cholestasis. The present study assessed the...

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Detalles Bibliográficos
Autores principales: Guo, Zhenya, Chen, Junze, Zeng, Yonglian, Wang, Zefeng, Yao, Mei, Tomlinson, Stephen, Chen, Bin, Yuan, Guandou, He, Songqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777082/
https://www.ncbi.nlm.nih.gov/pubmed/35069557
http://dx.doi.org/10.3389/fimmu.2021.785287