Cargando…

Complement Inhibition Alleviates Cholestatic Liver Injury Through Mediating Macrophage Infiltration and Function in Mice

BACKGROUND AND AIMS: Cholestatic liver injury (CLI), which is associated with inflammatory reactions and oxidative stress, is a serious risk factor for postoperative complications. Complement system is involved in a wide range of liver disorders, including cholestasis. The present study assessed the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Zhenya, Chen, Junze, Zeng, Yonglian, Wang, Zefeng, Yao, Mei, Tomlinson, Stephen, Chen, Bin, Yuan, Guandou, He, Songqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777082/ https://www.ncbi.nlm.nih.gov/pubmed/35069557 http://dx.doi.org/10.3389/fimmu.2021.785287

Ejemplares similares

The role of complement in nonalcoholic fatty liver disease
por: Guo, Zhenya, et al.
Publicado: (2022)

Editorial: New insights into the role of complement system in liver diseases
por: Guo, Zhenya, et al.
Publicado: (2023)

Identification and validation of potential diagnostic signature and immune cell infiltration for NAFLD based on cuproptosis-related genes by bioinformatics analysis and machine learning
por: Ouyang, Guoqing, et al.
Publicado: (2023)

Roles of the complement system in alcohol-induced liver disease
por: Zhou, Yi, et al.
Publicado: (2020)

The role of the complosome in health and disease
por: Xiao, Fang, et al.
Publicado: (2023)

Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis
por: Zhong, Fudi, et al.
Publicado: (2019)

Baicalein pre-treatment alleviates hepatic ischemia/reperfusion injury in mice by regulating the Nrf2/ARE pathway
por: Zhou, Yi, et al.
Publicado: (2021)

Inhibition of NLRP3-mediated crosstalk between hepatocytes and liver macrophages by geniposidic acid alleviates cholestatic liver inflammatory injury
por: Song, Meng, et al.
Publicado: (2022)

Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation
por: Zheng, Chaowen, et al.
Publicado: (2021)

Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis
por: Gong, Zizhen, et al.
Publicado: (2016)

The HVEM-BTLA Immune Checkpoint Restrains Murine Chronic Cholestatic Liver Injury by Regulating the Gut Microbiota
por: Kou, Yanbo, et al.
Publicado: (2022)

ERRγ suppression by Sirt6 alleviates cholestatic liver injury and fibrosis
por: Hao, Lihua, et al.
Publicado: (2020)

Complement in the Homeostatic and Ischemic Brain
por: Alawieh, Ali, et al.
Publicado: (2015)

FBXL19 promotes malignant behaviours by activating MAPK signalling and negatively correlates with prognosis in hepatocellular carcinoma
por: Xun, Min, et al.
Publicado: (2023)

Transcriptional profiling of pediatric cholestatic livers identifies three distinct macrophage populations
por: Taylor, Sarah A., et al.
Publicado: (2021)

The Role of Inflammation in Cholestatic Liver Injury
por: Chen, Jie, et al.
Publicado: (2023)

Complementing regeneration
por: Alawieh, Ali, et al.
Publicado: (2015)

Efficient complement-mediated clearance of immunosuppressed T cells by macrophages
por: Gankema, Angela A. F., et al.
Publicado: (2023)

Costunolide alleviated DDC induced ductular reaction and inflammatory response in murine model of cholestatic liver disease
por: Hao, Juan, et al.
Publicado: (2023)

Drainage of inflammatory macromolecules from the brain to periphery targets the liver for macrophage infiltration
por: Yang, Linlin, et al.
Publicado: (2020)

Bile acid-mediated signaling in cholestatic liver diseases
por: Zeng, Jing, et al.
Publicado: (2023)

A rare case of cefepime-induced cholestatic liver injury
por: Liao, Pei-Fei, et al.
Publicado: (2019)

Spermine Alleviates Acute Liver Injury by Inhibiting Liver-Resident Macrophage Pro-Inflammatory Response Through ATG5-Dependent Autophagy
por: Zhou, Shun, et al.
Publicado: (2018)

Polo-like kinase 1 is related with malignant characteristics and inhibits macrophages infiltration in glioma
por: Luo, Lin, et al.
Publicado: (2022)

Lactate-driven macrophage polarization in the inflammatory microenvironment alleviates intestinal inflammation
por: Zhou, Hai-Cun, et al.
Publicado: (2022)

Liver Transplantation for Patients with Cholestatic Liver Diseases
por: Schöning, Wenzel, et al.
Publicado: (2015)

The Gut-Liver Axis in Cholestatic Liver Diseases
por: Blesl, Andreas, et al.
Publicado: (2021)

Fibrotic Events in the Progression of Cholestatic Liver Disease
por: Wu, Hanghang, et al.
Publicado: (2021)

Fibrosis in Autoimmune and Cholestatic Liver Disease
por: Penz-Österreicher, Melitta, et al.
Publicado: (2011)

Update on pharmacotherapies for cholestatic liver disease
por: Ali, Ahmad H., et al.
Publicado: (2016)

Review: Pathogenesis of cholestatic liver diseases
por: Yokoda, Raquel T, et al.
Publicado: (2020)

Infiltration of LPAR5(+) macrophages in osteosarcoma tumor microenvironment predicts better outcomes
por: He, Yi, et al.
Publicado: (2022)

Conditional depletion of macrophages ameliorates cholestatic liver injury and fibrosis via lncRNA-H19
por: Tian, Xinbei, et al.
Publicado: (2021)

Modulation of the Complement System by Neoplastic Disease of the Central Nervous System
por: Yarmoska, Steven K., et al.
Publicado: (2021)

Adiponectin Alleviates Diet-Induced Inflammation in the Liver by Suppressing MCP-1 Expression and Macrophage Infiltration
por: Ryu, Jiyoon, et al.
Publicado: (2021)

Crosstalk between Gut Microbiota and Bile Acids in Cholestatic Liver Disease
por: Shi, Qingmiao, et al.
Publicado: (2023)

Complement Receptor-Mediated Phagocytosis Induces Proinflammatory Cytokine Production in Murine Macrophages
por: Acharya, Durga, et al.
Publicado: (2020)

The oxygen carrier M101 alleviates complement activation, which may be beneficial for donor organ preservation
por: Puissant-Lubrano, Bénédicte, et al.
Publicado: (2022)

Comparison of surgical outcomes among open, laparoscopic, and robotic pancreatoduodenectomy: a single-center retrospective study
por: Guo, Wei, et al.
Publicado: (2022)

MiR-130a-3p Alleviates Liver Fibrosis by Suppressing HSCs Activation and Skewing Macrophage to Ly6C(lo) Phenotype
por: Liu, Lei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_18v5nmslk1rk7bnitpto4oov6f