Genetic Blockade of NAAA Cell-specifically Regulates Fatty Acid Ethanolamides (FAEs) Metabolism and Inflammatory Responses

N-Acylethanolamine acid amidase (NAAA) is a lysosomal enzyme responsible for the hydrolysis of fatty acid ethanolamides (FAEs). However, the role of NAAA in FAEs metabolism and regulation of pain and inflammation remains mostly unknown. Here, we generated NAAA-deficient (NAAA(-/-)) mice using CRISPR...

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Detalles Bibliográficos
Autores principales: Xie, Xiaohua, Li, Yitian, Xu, Sennan, Zhou, Pan, Yang, Longhe, Xu, Yaping, Qiu, Yan, Yang, Yungang, Li, Yuhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777083/
https://www.ncbi.nlm.nih.gov/pubmed/35069223
http://dx.doi.org/10.3389/fphar.2021.817603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777083/
https://www.ncbi.nlm.nih.gov/pubmed/35069223
http://dx.doi.org/10.3389/fphar.2021.817603

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