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NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length

Deficiency of NEIL3, a DNA repair enzyme, has significant impact on mouse physiology, including vascular biology and gut health, processes related to aging. Leukocyte telomere length (LTL) is suggested as a marker of biological aging, and shortened LTL is associated with increased risk of cardiovasc...

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Detalles Bibliográficos
Autores principales: Karlsen, Tom Rune, Olsen, Maria B., Kong, Xiang Y., Yang, Kuan, Quiles-Jiménez, Ana, Kroustallaki, Penelope, Holm, Sverre, Lines, Glenn Terje, Aukrust, Pål, Skarpengland, Tonje, Bjørås, Magnar, Dahl, Tuva B., Nilsen, Hilde, Gregersen, Ida, Halvorsen, Bente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777121/
https://www.ncbi.nlm.nih.gov/pubmed/35079641
http://dx.doi.org/10.1016/j.bbrep.2022.101211