Calmodulin binding to the dehydrogenase domain of NADPH oxidase 5 alters its oligomeric state

Superoxide generated by NADPH Oxidase 5 (Nox5) is regulated by Ca(2+) through the interaction of its self-contained Ca(2+) binding domain and dehydrogenase domain (DH). Recently, calmodulin (CaM) has been reported to enhance the Ca(2+) sensitivity of Nox5 by binding to the CaM-binding domain sequenc...

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Detalles Bibliográficos
Autores principales: Smith, Dustin, Lloyd, Laura, Wei, Elaine, Radmanesh, Paria, Wei, Chin-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777244/
https://www.ncbi.nlm.nih.gov/pubmed/35079639
http://dx.doi.org/10.1016/j.bbrep.2021.101198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777244/
https://www.ncbi.nlm.nih.gov/pubmed/35079639
http://dx.doi.org/10.1016/j.bbrep.2021.101198

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