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Deep analysis of neuroblastoma core regulatory circuitries using online databases and integrated bioinformatics shows their pan-cancer roles as prognostic predictors

AIM: Neuroblastoma is a heterogeneous childhood cancer derived from the neural crest. The dual cell identities of neuroblastoma include Mesenchymal (MES) and Adrenergic (ADRN). These identities are conferred by a small set of tightly-regulated transcription factors (TFs) binding super enhancers, col...

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Detalles Bibliográficos
Autores principales: Jahangiri, Leila, Pucci, Perla, Ishola, Tala, Pereira, Joao, Cavanagh, Megan L., Turner, Suzanne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777518/
https://www.ncbi.nlm.nih.gov/pubmed/35201514
http://dx.doi.org/10.1007/s12672-021-00452-3