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Focal adhesion kinase inhibitor BI 853520 inhibits cell proliferation, migration and EMT process through PI3K/AKT/mTOR signaling pathway in ovarian cancer

Focal adhesion kinase (FAK) activation has been reported to be associated with cell progression and metastasis in a wide variety of cancer cells. Target treatment by inhibiting FAK has achieved remarkable effects in several cancers, but the effect in ovarian cancer has not been reported. In this stu...

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Detalles Bibliográficos
Autores principales: Li, Hong, Gao, Yizhi, Ren, Chenchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777525/
https://www.ncbi.nlm.nih.gov/pubmed/35201437
http://dx.doi.org/10.1007/s12672-021-00425-6