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Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial

IMPORTANCE: Aging is associated with a decline in mitochondrial function and reduced exercise capacity. Urolithin A is a natural gut microbiome–derived food metabolite that has been shown to stimulate mitophagy and improve muscle function in older animals and to induce mitochondrial gene expression...

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Detalles Bibliográficos
Autores principales: Liu, Sophia, D’Amico, Davide, Shankland, Eric, Bhayana, Saakshi, Garcia, Jose M., Aebischer, Patrick, Rinsch, Chris, Singh, Anurag, Marcinek, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777576/
https://www.ncbi.nlm.nih.gov/pubmed/35050355
http://dx.doi.org/10.1001/jamanetworkopen.2021.44279