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Time-Prolonged Release of Tumor-Targeted Protein–MMAE Nanoconjugates from Implantable Hybrid Materials

The sustained release of small, tumor-targeted cytotoxic drugs is an unmet need in cancer therapies, which usually rely on punctual administration regimens of non-targeted drugs. Here, we have developed a novel concept of protein–drug nanoconjugates, which are packaged as slow-releasing chemically h...

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Detalles Bibliográficos
Autores principales: Serna, Naroa, Falgàs, Aïda, García-León, Annabel, Unzueta, Ugutz, Núñez, Yáiza, Sánchez-Chardi, Alejandro, Martínez-Torró, Carlos, Mangues, Ramón, Vazquez, Esther, Casanova, Isolda, Villaverde, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777625/
https://www.ncbi.nlm.nih.gov/pubmed/35057088
http://dx.doi.org/10.3390/pharmaceutics14010192