Aggregatibacter actinomycetemcomitans as the Aetiological Cause of Rheumatoid Arthritis: What Are the Unsolved Puzzles?

Leukotoxin A (LtxA) is the major virulence factor of an oral bacterium known as Aggregatibacter actinomycetemcomitans (Aa). LtxA is associated with elevated levels of anti-citrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA) patients. LtxA targets leukocytes and triggers an influx of...

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Detalles Bibliográficos
Autores principales: Looh, Sung Cheng, Soo, Zoey May Pheng, Wong, Jia Jia, Yam, Hok Chai, Chow, Sook Khuan, Hwang, Jung Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777676/
https://www.ncbi.nlm.nih.gov/pubmed/35051027
http://dx.doi.org/10.3390/toxins14010050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777676/
https://www.ncbi.nlm.nih.gov/pubmed/35051027
http://dx.doi.org/10.3390/toxins14010050

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