The Compound (E)-2-Cyano-N,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases

The compound (E)-2-cyano-N,3-diphenylacrylamide (JMPR-01) was structurally developed using bioisosteric modifications of a hybrid prototype as formed from fragments of indomethacin and paracetamol. Initially, in vitro assays were performed to determine cell viability (in macrophage cultures), and it...

Descripción completa

Detalles Bibliográficos
Autores principales: da Silva, Pablo Rayff, do Espírito Santo, Renan Fernandes, Melo, Camila de Oliveira, Pachú Cavalcante, Fábio Emanuel, Costa, Thássia Borges, Barbosa, Yasmim Vilarim, e Silva, Yvnni M. S. de Medeiros, de Sousa, Natália Ferreira, Villarreal, Cristiane Flora, de Moura, Ricardo Olímpio, dos Santos, Vanda Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777680/
https://www.ncbi.nlm.nih.gov/pubmed/35057082
http://dx.doi.org/10.3390/pharmaceutics14010188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777680/
https://www.ncbi.nlm.nih.gov/pubmed/35057082
http://dx.doi.org/10.3390/pharmaceutics14010188

Ejemplares similares