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Ranolazine: An Old Drug with Emerging Potential; Lessons from Pre-Clinical and Clinical Investigations for Possible Repositioning

Ischemic heart disease is a significant public health problem with high mortality and morbidity. Extensive scientific investigations from basic sciences to clinics revealed multilevel alterations from metabolic imbalance, altered electrophysiology, and defective Ca(2+)/Na(+) homeostasis leading to l...

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Detalles Bibliográficos
Autores principales: Rouhana, Sarah, Virsolvy, Anne, Fares, Nassim, Richard, Sylvain, Thireau, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777683/
https://www.ncbi.nlm.nih.gov/pubmed/35056088
http://dx.doi.org/10.3390/ph15010031