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Unveiling of Pyrimidindinones as Potential Anti-Norovirus Agents—A Pharmacoinformatic-Based Approach

The RNA-dependent RNA polymerase (RdRp) receptor is an attractive target for treating human norovirus (HNV). A computer-aided approach like e-pharmacophore, molecular docking, and single point energy calculations were performed on the compounds retrieved from the Development Therapeutics Program (DT...

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Detalles Bibliográficos
Autores principales: Ebenezer, Oluwakemi, Damoyi, Nkululeko, Jordaan, Maryam A., Shapi, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777711/
https://www.ncbi.nlm.nih.gov/pubmed/35056692
http://dx.doi.org/10.3390/molecules27020380