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Metabolic Reprogramming of Glioblastoma Cells during HCMV Infection Induces Secretome-Mediated Paracrine Effects in the Microenvironment

Glioblastoma (GBM) is an aggressive primary central nervous system neoplasia with limited therapeutic options and poor prognosis. Following reports of cytomegalovirus (HCMV) in GBM tumors, the anti-viral drug Valganciclovir was administered and found to significantly increase the longevity of GBM pa...

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Detalles Bibliográficos
Autores principales: Harrison, Mark A. A., Hochreiner, Emily M., Benjamin, Brooke P., Lawler, Sean E., Zwezdaryk, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777757/
https://www.ncbi.nlm.nih.gov/pubmed/35062307
http://dx.doi.org/10.3390/v14010103