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Metabolic Reprogramming of Glioblastoma Cells during HCMV Infection Induces Secretome-Mediated Paracrine Effects in the Microenvironment
Glioblastoma (GBM) is an aggressive primary central nervous system neoplasia with limited therapeutic options and poor prognosis. Following reports of cytomegalovirus (HCMV) in GBM tumors, the anti-viral drug Valganciclovir was administered and found to significantly increase the longevity of GBM pa...
Autores principales: | Harrison, Mark A. A., Hochreiner, Emily M., Benjamin, Brooke P., Lawler, Sean E., Zwezdaryk, Kevin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777757/ https://www.ncbi.nlm.nih.gov/pubmed/35062307 http://dx.doi.org/10.3390/v14010103 |
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