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Identification of Cyclic Sulfonamides with an N-Arylacetamide Group as α-Glucosidase and α-Amylase Inhibitors: Biological Evaluation and Molecular Modeling

Diabetes mellitus (DM), a complicated metabolic disorder, is due to insensitivity to insulin function or reduction in insulin secretion, which results in postprandial hyperglycemia. α-Glucosidase inhibitors (AGIs) and α-amylase inhibitors (AAIs) block the function of digestive enzymes, which delays...

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Detalles Bibliográficos
Autores principales: Saddique, Furqan Ahmad, Ahmad, Matloob, Ashfaq, Usman Ali, Muddassar, Muhammad, Sultan, Sadia, Zaki, Magdi E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777765/
https://www.ncbi.nlm.nih.gov/pubmed/35056163
http://dx.doi.org/10.3390/ph15010106