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HIF-1α Negatively Regulates Irisin Expression Which Involves in Muscle Atrophy Induced by Hypoxia

Exposure to high altitude environment leads to skeletal muscle atrophy. As a hormone secreted by skeletal muscles after exercise, irisin contributes to promoting muscle regeneration and ameliorating skeletal muscle atrophy, but its role in hypoxia-induced skeletal muscle atrophy is still unclear. Ou...

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Detalles Bibliográficos
Autores principales: Liu, Shiqiang, Fu, Pengyu, Ning, Kaiting, Wang, Rui, Yang, Baoqiang, Chen, Jiahui, Xu, Huiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777935/
https://www.ncbi.nlm.nih.gov/pubmed/35055073
http://dx.doi.org/10.3390/ijms23020887