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An Oligomeric Sulfated Hyaluronan and Silk-Elastinlike Polymer Combination Protects against Murine Radiation Induced Proctitis

Semisynthetic glycosaminoglycan ethers (SAGEs) are short, sulfated hyaluronans which combine the natural properties of hyaluronan with chemical sulfation. In a murine model, SAGEs provide protection against radiation induced proctitis (RIP), a side effect of lower abdominal radiotherapy for cancer....

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Detalles Bibliográficos
Autores principales: Steinhauff, Douglas, Jensen, Mark Martin, Griswold, Ethan, Jedrzkiewicz, Jolanta, Cappello, Joseph, Oottamasathien, Siam, Ghandehari, Hamidreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777937/
https://www.ncbi.nlm.nih.gov/pubmed/35057068
http://dx.doi.org/10.3390/pharmaceutics14010175