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Inhibitory Effect of Etravirine, a Non-Nucleoside Reverse Transcriptase Inhibitor, via Anterior Gradient Protein 2 Homolog Degradation against Ovarian Cancer Metastasis

Anterior gradient protein 2 homolog (AGR2), an endoplasmic reticulum protein, is secreted in the tumor microenvironment. AGR2 is a member of the disulfide isomerase family, is highly expressed in multiple cancers, and promotes cancer metastasis. In this study, we found that etravirine, which is a no...

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Detalles Bibliográficos
Autores principales: Ly, Thanh Truong Giang, Yun, Jisoo, Ha, Jong-Seong, Kim, Yeon-Ju, Jang, Woong-Bi, Van Le, Thi Hong, Rethineswaran, Vinoth Kumar, Choi, Jaewoo, Kim, Jae-Ho, Min, Sang-Hyun, Lee, Dong-Hyung, Yang, Ju-Seok, Chung, Joo-Seop, Kwon, Sang-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777939/
https://www.ncbi.nlm.nih.gov/pubmed/35055132
http://dx.doi.org/10.3390/ijms23020944