Lignin Nanoparticles Deliver Novel Thymine Biomimetic Photo-Adducts with Antimelanoma Activity

We report here the synthesis of novel thymine biomimetic photo-adducts bearing an alkane spacer between nucleobases and characterized by antimelanoma activity against two mutated cancer cell lines overexpressing human Topoisomerase 1 (TOP1), namely SKMEL28 and RPMI7951. Among them, Dewar Valence pho...

Descripción completa

Detalles Bibliográficos
Autores principales: Gabellone, Sofia, Piccinino, Davide, Filippi, Silvia, Castrignanò, Tiziana, Zippilli, Claudio, Del Buono, Davide, Saladino, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777952/
https://www.ncbi.nlm.nih.gov/pubmed/35055101
http://dx.doi.org/10.3390/ijms23020915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777952/
https://www.ncbi.nlm.nih.gov/pubmed/35055101
http://dx.doi.org/10.3390/ijms23020915

Ejemplares similares