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Lignin Nanoparticles Deliver Novel Thymine Biomimetic Photo-Adducts with Antimelanoma Activity

We report here the synthesis of novel thymine biomimetic photo-adducts bearing an alkane spacer between nucleobases and characterized by antimelanoma activity against two mutated cancer cell lines overexpressing human Topoisomerase 1 (TOP1), namely SKMEL28 and RPMI7951. Among them, Dewar Valence pho...

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Detalles Bibliográficos
Autores principales:	Gabellone, Sofia, Piccinino, Davide, Filippi, Silvia, Castrignanò, Tiziana, Zippilli, Claudio, Del Buono, Davide, Saladino, Raffaele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777952/ https://www.ncbi.nlm.nih.gov/pubmed/35055101 http://dx.doi.org/10.3390/ijms23020915

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