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A Multidrug Approach to Modulate the Mitochondrial Metabolism Impairment and Relative Oxidative Stress in Fanconi Anemia Complementation Group A

Fanconi Anemia (FA) is a rare recessive genetic disorder characterized by aplastic anemia due to a defective DNA repair system. In addition, dysfunctional energy metabolism, lipid droplets accumulation, and unbalanced oxidative stress are involved in FA pathogenesis. Thus, to modulate the altered me...

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Detalles Bibliográficos
Autores principales: Cappelli, Enrico, Bertola, Nadia, Bruno, Silvia, Degan, Paolo, Regis, Stefano, Corsolini, Fabio, Banelli, Barbara, Dufour, Carlo, Ravera, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777953/
https://www.ncbi.nlm.nih.gov/pubmed/35050128
http://dx.doi.org/10.3390/metabo12010006