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Effect of MDI Actuation Timing on Inhalation Dosimetry in a Human Respiratory Tract Model

Accurate knowledge of the delivery of locally acting drug products, such as metered-dose inhaler (MDI) formulations, to large and small airways is essential to develop reliable in vitro/in vivo correlations (IVIVCs). However, challenges exist in modeling MDI delivery, due to the highly transient mul...

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Detalles Bibliográficos
Autores principales: Talaat, Mohamed, Si, Xiuhua, Xi, Jinxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777964/
https://www.ncbi.nlm.nih.gov/pubmed/35056118
http://dx.doi.org/10.3390/ph15010061