Cargando…

In Silico Prediction and Design of Uropathogenic Escherichia coli Alpha-Hemolysin Generate a Soluble and Hemolytic Recombinant Toxin

The secretion of α-hemolysin by uropathogenic Escherichia coli (UPEC) is commonly associated with the severity of urinary tract infections, which makes it a predictor of poor prognosis among patients. Accordingly, this toxin has become a target for diagnostic tests and therapeutic interventions. How...

Descripción completa

Detalles Bibliográficos
Autores principales: Caetano, Bruna De Lucca, Domingos, Marta de Oliveira, da Silva, Miriam Aparecida, da Silva, Jessika Cristina Alves, Polatto, Juliana Moutinho, Montoni, Fabio, Iwai, Leo Kei, Pimenta, Daniel Carvalho, Vigerelli, Hugo, Vieira, Paulo Cesar Gomes, Ruiz, Rita de Cassia, Patané, José Salvatore, Piazza, Roxane Maria Fontes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778037/
https://www.ncbi.nlm.nih.gov/pubmed/35056621
http://dx.doi.org/10.3390/microorganisms10010172