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In Silico Prediction and Design of Uropathogenic Escherichia coli Alpha-Hemolysin Generate a Soluble and Hemolytic Recombinant Toxin
The secretion of α-hemolysin by uropathogenic Escherichia coli (UPEC) is commonly associated with the severity of urinary tract infections, which makes it a predictor of poor prognosis among patients. Accordingly, this toxin has become a target for diagnostic tests and therapeutic interventions. How...
Autores principales: | Caetano, Bruna De Lucca, Domingos, Marta de Oliveira, da Silva, Miriam Aparecida, da Silva, Jessika Cristina Alves, Polatto, Juliana Moutinho, Montoni, Fabio, Iwai, Leo Kei, Pimenta, Daniel Carvalho, Vigerelli, Hugo, Vieira, Paulo Cesar Gomes, Ruiz, Rita de Cassia, Patané, José Salvatore, Piazza, Roxane Maria Fontes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778037/ https://www.ncbi.nlm.nih.gov/pubmed/35056621 http://dx.doi.org/10.3390/microorganisms10010172 |
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