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A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model

Nanosized drug delivery systems targeting transporters of the blood-brain barrier (BBB) are promising carriers to enhance the penetration of therapeutics into the brain. The expression of solute carriers (SLC) is high and shows a specific pattern at the BBB. Here we show that targeting ligands ascor...

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Detalles Bibliográficos
Autores principales: Veszelka, Szilvia, Mészáros, Mária, Porkoláb, Gergő, Szecskó, Anikó, Kondor, Nóra, Ferenc, Györgyi, Polgár, Tamás F., Katona, Gábor, Kóta, Zoltán, Kelemen, Lóránd, Páli, Tibor, Vigh, Judit P., Walter, Fruzsina R., Bolognin, Silvia, Schwamborn, Jens C., Jan, Jeng-Shiung, Deli, Mária A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778049/
https://www.ncbi.nlm.nih.gov/pubmed/35056983
http://dx.doi.org/10.3390/pharmaceutics14010086