A New Epitope Selection Method: Application to Design a Multi-Valent Epitope Vaccine Targeting HRAS Oncogene in Squamous Cell Carcinoma

We developed an epitope selection method for the design of MHC targeting peptide vaccines. The method utilizes predictions for several clinical checkpoint filters, including binding affinity, immunogenicity, antigenicity, half-life, toxicity, IFNγ release, and instability. The accuracy of the predic...

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Detalles Bibliográficos
Autores principales: Savsani, Kush, Jabbour, Gabriel, Dakshanamurthy, Sivanesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778118/
https://www.ncbi.nlm.nih.gov/pubmed/35062725
http://dx.doi.org/10.3390/vaccines10010063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778118/
https://www.ncbi.nlm.nih.gov/pubmed/35062725
http://dx.doi.org/10.3390/vaccines10010063

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