Novel Transcriptional and Translational Biomarkers of Tularemia Vaccine Efficacy in a Mouse Inhalation Model: Proof of Concept

Francisella tularensis subspecies tularensis (Ftt) is extremely virulent for humans when inhaled as a small particle aerosol (<5 µm). Inhalation of ≥20 viable bacteria is sufficient to initiate infection with a mortality rate ≥30%. Consequently, in the past, Ftt became a primary candidate for bio...

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Detalles Bibliográficos
Autores principales: Liu, Qing Yan, Leclerc, Sonia, Pan, Youlian, Liu, Ziying, Stark, Felicity, Conlan, Joseph Wayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778127/
https://www.ncbi.nlm.nih.gov/pubmed/35056485
http://dx.doi.org/10.3390/microorganisms10010036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778127/
https://www.ncbi.nlm.nih.gov/pubmed/35056485
http://dx.doi.org/10.3390/microorganisms10010036

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